Mutational signatures
CHARACTERISTIC COMBINATION OF MUTATION TYPES ARISING FROM A SPECIFIC MUTAGENESIS PROCESS
User:Mylinhthibodeau/sandbox/Mutational Signatures in Cancer; Draft:Mutational Signatures in Cancer; Mutational Signatures in Cancer; Mutational signatures in cancer
Mutational signatures are characteristic combinations of mutation types arising from specific mutagenesis processes such as DNA replication infidelity, exogenous and endogenous genotoxin exposures, defective DNA repair pathways, and DNA enzymatic editing.